Treatments for Neuroblastoma in Children

Your Child's Care Begins Here

Our Haworth Innovative Therapeutics Clinic offers young patients access to clinical trials and the latest treatment strategies for neuroblastoma. We offer phase I and phase II trials that include a sophisticated gene analysis of a tumor sample so that treatment can be designed specifically for each individual child. 

Our pediatric oncology research program oversees the Beat Childhood Cancer consortium, which includes 33 hospitals across the United States. Within the consortium, we enrolled 203 children on our clinical trials in 2017. Together we successfully completed a pilot study of children with high-risk Neuroblastoma using precision medicine at diagnosis combined with standard of care and the addition of DFMO as maintenance therapy. This study showed the safety and feasibility of this approach and was approved to move forward in a Phase II clinical trial.

If surgery is needed as part of treatment, we collaborate with our pediatric surgeons, who are skilled at helping kids of all ages.

Treatments We Provide

Chemotherapy

Your child will likely require chemotherapy before and/or after surgery. If the primary tumor cannot be removed surgically, chemotherapy may become the main treatment.

Radiation Therapy

Radiation uses powerful X-rays to destroy neuroblastoma cells remaining after chemotherapy and surgery.

Immunotherapy ("Antibody Therapy")

Special antibodies are used to direct and stimulate the immune system so it can attack the neuroblastoma cancer cells.

Surgery

Most children with neuroblastoma will need the primary tumor removed surgically. Surgery is sometimes the only treatment needed if tumors are small and the cancer hasn't spread.

Retinoid Therapy

In children with high-risk neuroblastoma, a drug related to vitamin A can help cancer cells turn into mature nerve cells, and prevent the cancer from growing or spreading.

Clinical Trials for Neuroblastoma

Helen DeVos Children's Hospital leads the Beat Childhood Cancer consortium, a group of children's hospitals and universities working to develop new ways to treat neuroblastoma. Your child may be a candidate for our phase I and II clinical trials.