COVID-19 Monoclonal Antibody Treatment

If you have a positive COVID-19 test and are experiencing mild to moderate symptoms, you might be eligible for monoclonal antibody therapy. Spectrum Health West Michigan operates an infusion clinic at Spectrum Health Blodgett Hospital that uses monoclonal antibodies for the treatment of COVID-19 under a U.S. Food and Drug Administration Emergency Use Authorization. 

To be considered for this treatment option, patients must be 12 years of age or older and meet the following initial criteria:

  • Positive COVID-19 test


  • COVID-19 related symptoms have been present for less than 10 days


  • Patient is not hospitalized


  • You have one or more risk factors for disease progression. These risk factors are determined by your a COVID-19 infusion clinic provider over the phone.

To schedule an appointment, please contact us at 616.391.0351. Patients at Spectrum Health Lakeland should talk with their primary care provider or click here to learn more. Click here for fact sheets as well as an FAQ from the U.S. Food and Drug Administration.*

*Statements required by the U.S. Food and Drug Administration

  • Casirivimab and imdevimab treatment has not been approved but has been authorized for emergency use by FDA under an EUA, to treat mild to moderate COVID19 in adults and pediatric patients (12 years of age and older weighing at least 40 kg) with positive results of direct SARS-CoV-2 viral testing, and who are at high risk for progressing to severe COVID-19 and/or hospitalization.
  • The emergency use of casirivimab and imdevimab is only authorized for the duration of the declaration that circumstances exist justifying the authorization of the emergency use of drugs and biological products during the COVID-19 pandemic under Section 564(b)(1) of the Act, 21 U.S.C. § 360bbb-3(b)(1), unless the declaration is terminated, or authorization revoked sooner.

Frequently Asked Questions

Mild symptoms usually mean that the virus is present only in your upper airways and blood and has not caused any damage to your vital organs such as the lungs. This is the ideal time for monoclonal antibodies to bind and kill the virus. If the virus enters your organs and causes severe symptoms, monoclonal antibodies may not be as active and able to stop disease progression.

Response to therapy is individual and ranges from a few days to a week.

Yes; you can get the COVID-19 vaccine, and we encourage you to get vaccinated. The Centers for Disease Control and Prevention recommends waiting 90 days after receiving monoclonal antibodies since monoclonal antibodies and vaccine can interact and decrease long-term protection.

We recommend waiting 90 days after you receive monoclonal antibodies. Then repeat the first dose of the vaccine followed by the second dose at the appropriate interval.

No; at this point. The U.S. Food and Drug Administration does not recommend repeating vaccine in this situation.

No; after receiving monoclonal antibodies, you should not receive convalescent plasma. MAB (or monoclonal antibodies) and plasma work the same way, and convalescent plasma is not likely to provide any additional benefits.

Yes; you can receive all medications for COVID-19 other than convalescent plasma.

No; your quarantine time will remain the same. Despite the anticipated improvement in your symptoms, you will still be contagious. Please continue isolating, wearing a mask and practicing good handwashing.

Yes; you may drive yourself to the appointment if you are feeling well enough. However, we do recommend having a backup plan for a ride home in the event you experience a reaction to the monoclonal antibodies and are required to receive a dose of Benadryl, which may make you sleepy. If this is an issue for your situation, we will work with you and this does not need to limit your ability to get the infusion.

Yes; the medication itself is covered and your insurance company is billed for an infusion center cost. At Spectrum Health, we want to ensure that all patients who would like to receive this infusion are able to and not limited by financial constraints.

No; monoclonal antibody infusion not covered in full by your insurance company will be written off and not balance billed to you. However, we have noticed many insurance companies are paying for monoclonal antibody infusion treatment in full.

Here are billing codes for this treatment:



CPT Short Descriptor

Labeler Name

Vaccine/Procedure Name



Eli Lilly

Injection, bamlanivimab, 700 mg


Bamlanivimab-xxxx infusion

Eli Lilly

Intravenous infusion, bamlanivimab-xxxx, includes infusion and post administration monitoring


Casirivimab and imdevimab


Injection, casirivimab and imdevimab, 2400 mg


Casirivi and imdevi infusion


Intravenous infusion, casirivimab and imdevimab includes infusion and post administration monitoring

If you do not have insurance, we can help you access funds available to Spectrum Health that can help cover the cost of monoclonal antibody infusion treatment. Any remaining infusion cost will not be billed to you.