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Total Body Irradiation

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When radiation is delivered to the whole body, it is called total body irradiation (TBI). TBI is performed to suppress a patient's immune system and prevent rejection of donor bone marrow prior to a bone marrow transplant, or to destroy abnormal cells that escape other therapies (such as surgery, chemotherapy or local irradiation).

For example, total body irradiation is used at Spectrum Health as a component of the preparatory regimen for both adult and pediatric bone marrow transplant.